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Discussion:2019 Novel Corona Virus (Covid19) and It's Political Ramifications #3


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10 hours ago, Ridgerunner said:

I just read a Reuters story from May 19 with the headline "Sweden tops Europe covid-19 deaths per capita over last seven days".  But within the story is the following statement, "Over the course of the pandemic Sweden still has had fewer deaths per capita than the United Kingdom, Spain, Italy, Belgium and France..."

When you start comparing country's mortality rates it is very difficult as so many factors vary in each country and you can prove or disaprove anything with numbers and statistics. i am not going to even try and make sense of any of the numbers as there are so many variations within the population and behaviour between country's that direct comparisons are impossible in my opinion. Take Germany for example they look to have out performed everyone, especially in Europe, but i doubt if their healthcare system is any better or worse than any other within reason. In a light hearted mode perhaps their figures were provided by volkswagon lol.

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4 minutes ago, Robwin said:

When you start comparing country's mortality rates it is very difficult as so many factors vary in each country and you can prove or disaprove anything with numbers and statistics. i am not going to even try and make sense of any of the numbers as there are so many variations within the population and behaviour between country's that direct comparisons are impossible in my opinion. Take Germany for example they look to have out performed everyone, especially in Europe, but i doubt if their healthcare system i any better or worse than any other within reason. In a light hearted mode perhaps their figures were provided by volkswagon lol.

That's why I say it will take at least five years to accurately judge what was the proper strategy.  It seems one common mistake made by most countries was not properly protecting nursing homes from covid-19. 

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30 minutes ago, Ridgerunner said:

That's why I say it will take at least five years to accurately judge what was the proper strategy.  It seems one common mistake made by most countries was not properly protecting nursing homes from covid-19. 

Whilst that may be true to a point what the hell were the care homes management doing about it after all they get a shed load of money from the dear old residents to be looked after properly. These homes management seem to have got away with bloody murder and just blaming it on the goverments. Sorry but i do feel very strongly about this.

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2 hours ago, Robwin said:

Whilst that may be true to a point what the hell were the care homes management doing about it after all they get a shed load of money from the dear old residents to be looked after properly. These homes management seem to have got away with bloody murder and just blaming it on the goverments. Sorry but i do feel very strongly about this.

My daughter is a care assistant in a care home run by the Royal Blind in Edinburgh.They sadly had a few deaths but she said although they had minimal PPE problems any infection had to be brought in from staff or necessary other visitors.Her opinion as we have all heard repeatedly is testing of anyone entering the building should have been the number one priority.A testing system was eventually put in place(thankfully she was negative) and the care home has been Covid free for just over 2 weeks now.Long may it continue.

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A drug, anakinra, originally intended for rheumatic diseases, gives "encouraging" results for severe forms of Covid-19 disease by reducing the risk of death and the need to be put on a ventilator in intensive care, according to a French study that offers a ray of hope. "The significant reduction in mortality associated with the use of anakinra for Covid-19 in this study is encouraging in these difficult times," writes rheumatologist Randy Cron of the University of Alabama (Birmingham, United States) in the specialist journal The Lancet Rheumatology where the study appears. He underlines the "favorable safety profile" of this drug well known to rheumatologists.

The goal is to counter the "cytokine storm", an uncontrolled inflammatory reaction implicated in severe forms of Covid-19 pneumonia, leading to acute respiratory distress syndrome (ARDS). A situation where the lungs do not provide enough oxygen to the vital organs, which requires the assistance of artificial ventilation with the use of a respirator. More specifically, anakinra targets, to block, one of the cytokines involved in this "inflammatory storm", interleukin-1 (IL-1).

According to the medical team, Thomas Huet and his colleagues, from the Paris Saint-Joseph Hospital Group (GHPSJ), the administration by subcutaneous injection for ten days of anakinra (trade name: Kineret), to 52 patients with 'a severe form of COVID-19 allowed a' statistically significant reduction in the risk of death and of going into intensive care for respiratory assistance by mechanical ventilation '. A quarter of patients treated with anakinra were transferred to intensive care or died, compared to almost 73% of those who did not have this biotherapy. The comparison group consisted of 44 patients who had previously been treated in the same institution.

In the group receiving anakinra, a rapid decrease in oxygen requirements was also observed after 7 days of treatment. "In the absence of access to therapeutic trials including immunomodulatory drugs for our patients, the decision (...) taken to offer anakinra, according to severity criteria decided in a consensual and a priori manner, quickly changed the face of the disease indoors, ”explains Professor Jean-Jacques Mourad, co-signatory of the study. "The profit was palpable on a daily basis," he said.

"There are currently a dozen clinical trials exploring the blockage of cytokine IL-1 associated with Covid-19 inflammatory storm syndrome," writes Dr. Randy Cron. Three small series of cases (including one from Italy) reported that anakinra benefited patients with COVID-19. "But this study provides the most convincing evidence to date that anakinra can benefit patients suffering from the cytokine storm syndrome associated with Covid-19," he continues. "Pending results of controlled trials, anakinra gives hope to those severely affected by Covid-19," adds Dr. Cron.

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13 hours ago, Robwin said:

Whilst that may be true to a point what the hell were the care homes management doing about it after all they get a shed load of money from the dear old residents to be looked after properly. These homes management seem to have got away with bloody murder and just blaming it on the goverments. Sorry but i do feel very strongly about this.

Maybe that was the intention of tthose in power in the government.  Isolate the most vulnerable and whatever happens, so be it,  because most are a drain to the social financial support systems anyway. 😏 (Our New York governor Cuomo did just that) 😠

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1 hour ago, moos54 said:

A drug, anakinra, originally intended for rheumatic diseases, gives "encouraging" results for severe forms of Covid-19 disease by reducing the risk of death and the need to be put on a ventilator in intensive care, according to a French study that offers a ray of hope. "The significant reduction in mortality associated with the use of anakinra for Covid-19 in this study is encouraging in these difficult times," writes rheumatologist Randy Cron of the University of Alabama (Birmingham, United States) in the specialist journal The Lancet Rheumatology where the study appears. He underlines the "favorable safety profile" of this drug well known to rheumatologists.

The goal is to counter the "cytokine storm", an uncontrolled inflammatory reaction implicated in severe forms of Covid-19 pneumonia, leading to acute respiratory distress syndrome (ARDS). A situation where the lungs do not provide enough oxygen to the vital organs, which requires the assistance of artificial ventilation with the use of a respirator. More specifically, anakinra targets, to block, one of the cytokines involved in this "inflammatory storm", interleukin-1 (IL-1).

According to the medical team, Thomas Huet and his colleagues, from the Paris Saint-Joseph Hospital Group (GHPSJ), the administration by subcutaneous injection for ten days of anakinra (trade name: Kineret), to 52 patients with 'a severe form of COVID-19 allowed a' statistically significant reduction in the risk of death and of going into intensive care for respiratory assistance by mechanical ventilation '. A quarter of patients treated with anakinra were transferred to intensive care or died, compared to almost 73% of those who did not have this biotherapy. The comparison group consisted of 44 patients who had previously been treated in the same institution.

In the group receiving anakinra, a rapid decrease in oxygen requirements was also observed after 7 days of treatment. "In the absence of access to therapeutic trials including immunomodulatory drugs for our patients, the decision (...) taken to offer anakinra, according to severity criteria decided in a consensual and a priori manner, quickly changed the face of the disease indoors, ”explains Professor Jean-Jacques Mourad, co-signatory of the study. "The profit was palpable on a daily basis," he said.

"There are currently a dozen clinical trials exploring the blockage of cytokine IL-1 associated with Covid-19 inflammatory storm syndrome," writes Dr. Randy Cron. Three small series of cases (including one from Italy) reported that anakinra benefited patients with COVID-19. "But this study provides the most convincing evidence to date that anakinra can benefit patients suffering from the cytokine storm syndrome associated with Covid-19," he continues. "Pending results of controlled trials, anakinra gives hope to those severely affected by Covid-19," adds Dr. Cron.

Now if Macron touts this drug as a possible cure--that is ok, but don't let President Trump hear about it and start touting it---because everyone will deny it works.  😏

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5 minutes ago, happyone said:

Now if Macron touts this drug as a possible cure--that is ok, but don't let President Trump hear about it and start touting it---because everyone will deny it works.  😏

Macron is smarter, he will let his health minister go to the fire in his place :biggrin:

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21 hours ago, letsdothis said:

If there was ever any question that this virus would miraculously
disappear with the heat, take a look at what's happening in Brazil
right now, whose average annual temp is in the 70sF (21sC).

image.png.6cafcc0765ba32f85b7574c8f9166103.png

Yep a complete load of bollocks that heat theory and it ain't exactly freezing in the UK right now either. 25 deg C today very hot in the sun lol

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44 minutes ago, Robwin said:

Yep a complete load of bollocks that heat theory and it ain't exactly freezing in the UK right now either. 25 deg C today very hot in the sun lol

Just goes to show the heat is not going to drive this virus away. Until a vaccine is in place the world is stuck with what it delivers.to them.  It's going to be pure hell if a second wave hits.  

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